Friday, March 04, 2005

Paxil vs. Natural Remedies

Jenny Thompson at HSI came up with this one. You might like to subscribe to her great newsletter.

---

The medical mainstream HATES this kind of thing.

In a recent trial that tested St. John's wort against the selective serotonin reuptake inhibitor (SSRI) paroxetine (better known by its U.S. brand name Paxil), St. John's wort produced better results and fewer adverse side effects.

Over a six-week study period, 122 patients with moderate to severe depression took a 900 mg St. John's wort extract daily, and 122 similar patients took 20 mg daily dose of Paxil. Results showed that about half the subjects in the St. John's wort group experienced relief from depression, while only about one-third of the Paxil subjects experienced relief.

As reported in the British Medical Journal (BMJ), about 170 adverse side effects occurred in the St. John's wort group, and nearly 270 side effects in the Paxil group. In both groups, stomach disorders were the most common complaint.

These results aren't a complete surprise. We've seen St. John's wort perform better with fewer side effects when pitted against pharmaceutical SSRIs in previous studies (although usually in subjects with light to moderate depression). Yet, what I found most interesting in this case were two comments about the study posted on the BMJ web site.

The first comment comes from Tim Watkins, the director of the Depression Alliance in the UK. He says he detects a hidden agenda in the study because the researchers (funded by a manufacturer of herbal remedies) chose Paxil instead of another SSRI. Paxil, he points out, has the worst reputation for side effects in this class of drugs. He says the researchers "must have known" that St. John's wort would produce fewer side effects than other SSRIs.

I can't agree that the researchers "must have known" how the side effects would stack up. These studies have a way of often producing surprise results. Just look at all those HRT studies that blew up in the researchers' faces.

And don't feel too sorry for poor beleaguered Paxil. GlaxoSmithKline, the maker of Paxil, reports that the drug brought in more than $2 billion in sales last year. In other words, there are a LOT of Paxil users out there. So in spite of the unfairness perceived by Mr. Watkins, the trial actually provides a service to any Paxil user who may be suffering from some of the more severe long-term side effects that have been associated with the drug.

The second BMJ comment comes from Jane Robertson, a reader in Australia. Jane is not a health professional, but she is a St. John's wort user. She writes that after spending 20 years in counseling to address chronic mild depression, she began using St. John's wort three years ago, and is now "leading a mentally healthy life without the agonized thinking I spent so long trying to sort out." She adds that her life has "been changed" by St. John's wort and is grateful that extracts of the herb are available over the counter.

'Nuff said. I will add, however, that St. John's wort should be taken with caution, especially by those who are also taking prescription drugs. St. John's wort has been shown to interfere with the effectiveness of some drugs. It is also critical that you not take yourself off of an SSRI without working with your doctor, especially if you are planning to substitute with St. John's wort or any other herbal or dietary supplement.

14 comments:

Deb said...

Hi Don, I am researching natural healing (and related subjects) and came across your post, Paxil vs. Natural Remedies. You probably know how easy it can be to get sidetracked online! Just wanted to say that I found your blog quite interesting and wanted to wish you all the best. Thanks! Deb http://www.herbsandnaturalremedies.com

Deb said...

Hi Don, I am researching natural remedies (and related subjects) and came across your post, Paxil vs. Natural Remedies. You probably know how easy it can be to get sidetracked online! Just wanted to say that I found your blog quite interesting and wanted to wish you all the best. Thanks! Deb http://www.herbsandnaturalremedies.com

Rita Kennon said...

Hey Don, How's everything going? I just thought I'd let you know how informative I found natural health solutions as I was searching today for new information for http://www.alternativehealthreporter.com. Paxil vs. Natural Remedies was very thought provoking, and I want you to know that I really enjoyed reading the post. Thanks!

Deb said...

Hi Don, I am researching herbs (and related subjects) and came across your post, Paxil vs. Natural Remedies. You probably know how easy it can be to get sidetracked online! Just wanted to say that I found your blog quite interesting and wanted to wish you all the best. Thanks! Deb http://www.herbsandnaturalremedies.com

Deb said...

Hi Don, I am researching natural healing (and related subjects) and came across your post, Paxil vs. Natural Remedies. You probably know how easy it can be to get sidetracked online! Just wanted to say that I found your blog quite interesting and wanted to wish you all the best. Thanks! Deb http://www.herbsandnaturalremedies.com

Rosita said...

Hello Don, Although Paxil vs. Natural Remedies wasn't exactly what I was searching for, it definitely grabbed my attention. I see now why I found your web page when I was looking for healthy weight loss related information. I'm glad that I stopped by, even though I didn't find exactly what I wanted. Thanks for the very informative post! http://www.alternativehealthreporter.com

Real Busy said...

Don, Paxil vs. Natural Remedies was very intriguing info. Very interesting! In my search for information on alternative health product to add to http://www.alternativehealthreporter.com I ran across your post. I appreciate the good read. I will definitely be back to check this site out again.

Working From Home said...

You Have A Very Good Blog!!!

Welcome to visit my vitamin nutritional supplement site which has much of all the vitamin nutritional supplement related stuff. Click here: vitamin nutritional supplement


I also recommend you check out the following online income opportunities and powerful marketing tools helping webmasters and online businesses to succeed online:
Business Opportunities Business websites for sale
Income$3600 Per Month Income for Life
Egold Free egold account
AsianPay Earn 4% for 6 Levels Online Payment System
Commission Earn big money
Email marketing Email 700 millions Free plus 100% resale right
Resale Earn cash income 100% resale
Resell Rights $6 investment only for an international business
Cash Income Earn commission income
Email Marketing Email 1000s of PayPal members for $12 per year
Ecurrencies Get your free eForexGold website and earn referral commission
Perfect Income Opportunities
Family Income News
Blog Blaster
Domains Hosting
Auto Ad Submitter
Email List
Web Traffic
Instant Booster Traffic for Free
Sitesell Website
Nutritional Supplements
Netsuitestore
Native Remedies
Anti Aging
Home Based Business
Domains Lowest cost domains and hosting

Rita Kennon said...

Hello Don, Although Paxil vs. Natural Remedies wasn't exactly what I was searching for, it definitely grabbed my attention. I see now why I found your web page when I was looking for alternative health product related information. I'm glad that I stopped by, even though I didn't find exactly what I wanted. Thanks for the very informative post! http://www.alternativehealthreporter.com

Nevada News said...

breast enhancers stimulate the tissue under the breast to grow again. The results are permanent. You CAN grow bigger fuller breasts with this. i

Annette Marco said...

Hey thanks- Breast Enhancercame with a free gift.

BBW said...

Does a breast enhancer need anything to go with it? Am I supposed to eat anything or not eat anything while I am taking it?

Dahunter said...

Hey how are you doing? just letting you know that someone from Central America read your blog!
If you feel like visiting mine:
currency trading tip
Regards,
Charles

val said...

Hi, I was searching the web looking for information related to Male Enhancement pills and i can across your site. I wanted to share my experience in what I have found on the web related to Male Enhancement pills . I found a site with great list of products all related to herbal remedies. You might check it Herbal Drugs Alternatives http://www.herbaldrugalternative.com, I found it quite useful with some really great products.